In 2003, Inserm introduced a new partnership policy with patient associations by creating the “GRAM”, a brainstorming group composed of 50% associations, to reinforce their role in patient information, clinical research and research programs within Inserm. The actions brought out are coordinated and implemented by the “Mission Associations Research & Society”, lead by Bernadette Bréant, researcher at Inserm. This network between Inserm and more than 500 patient associations covers the whole range of existing diseases. The core of our missions aim at bringing closer researchers and patient associations. The actions include training workshops on scientific issues or controversial topics (vaccination), organization of patients-researchers meetings in the Inserm laboratories, debate meetings, national Great Meetings in prestigious public places to bring together patients, researchers and policy makers and ultimately coordinating a retired scientists network and working groups, like the clinical research readers committee or the Alcohol Inserm working group.